Document Type

Article

Source Publication Title

Mathematical Sciences and Engineering

First Page

687

Last Page

717

Abstract

A classical epidemiological framework is used to provide a preliminary cost analysis of the effects of quarantine and isolation on the dynamics of infectious diseases for which no treatment or immediate diagnosis tools are available. Within this framework we consider the cost incurred from the implementation of three types of dynamic control strategies. Taking the context of the 2003 SARS outbreak in Hong Kong as an example, we use a simple cost function to compare the total cost of each mixed (quarantine and isolation) control strategy from a public health resource allocation perspective. The goal is to extend existing epi-economics methodology by developing a theoretical framework of dynamic quarantine strategies aimed at emerging diseases, by drawing upon the large body of literature on the dynamics of infectious diseases. We find that the total cost decreases with increases in the quarantine rates past a critical value, regardless of the resource allocation strategy. In the case of a manageable outbreak resources must be used early to achieve the best results whereas in case of an unmanageable outbreak, a constant-effort strategy seems the best among our limited plausible sets.

Disciplines

Mathematics | Physical Sciences and Mathematics

Publication Date

7-1-2010

Language

English

Comments

The research is partially supported by NSA (DOD grant H98230-05-1-0097), NSF (DMS- 0502349 and DMS-0817789), the Office of the Provost of Arizona State University and Norman Hackerman (ARP grant 003656-0144-2007).

Available for download on Wednesday, January 01, 3000

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