Author

Ying Zhang

Graduation Semester and Year

2011

Language

English

Document Type

Dissertation

Degree Name

Doctor of Philosophy in Chemistry

Department

Chemistry and Biochemistry

First Advisor

Daniel W Armstrong

Abstract

Enantiomeric separations are of great interest in the pharmaceutical, biotechnology and agrochemical industries due to the different therapeutic effects of enantiomers. Because of the high efficiency, sensitivity and simplicity, chiral gas chromatography has been widely applied to separate enantiomers that are volatile and thermally stable. In this dissertation, a group of novel chiral selectors based on cyclofructans for gas chromatography is developed and their enantioselective properties are evaluated.Room temperature ionic liquids (ILs) have been used as gas chromatographic stationary phase due to their unique physical properties in achiral separations. A series of trigonal tricationic ILs are synthesized, characterized and used as achiral gas chromatographic stationary phases. A rapid, efficient quantification method for water in solvents or solvents in water was developed using IL columns.High performance liquid chromatography is another prevalently used technique for separations. In this dissertation, methods are developed to separate and identify antioxidants from rosemary. The stabilities of these antioxidants are investigated.

Disciplines

Chemistry | Physical Sciences and Mathematics

Comments

Degree granted by The University of Texas at Arlington

Included in

Chemistry Commons

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