Graduation Semester and Year
Summer 2024
Document Type
Dissertation
Degree Name
Doctor of Philosophy in Biomedical Engineering
Department
Bioengineering
First Advisor
Dr. Justyn Jaworski
Second Advisor
Dr. Kytai T. Nguyen
Third Advisor
Dr. Cesar Torres
Abstract
Polydiacetylene based materials have been used for a variety of liquid phase sensing applications. There remains a need for low cost, easy-to-read gas phase sensors for continuous monitoring of physiological parameters and environmental hazards at work or at home. Such sensors could have applications in everyday life, for example as point-of-care or at home testing devices to enable early detection of disease to reduce healthcare costs. Making accessible and non-invasive technologies for monitoring of health and health risks provides individuals with the ability to be proactive in regard to their health and safety. In other examples, environmental monitoring systems could be used to detect harmful pollutants through direct detection of compounds in the air or water supply. Here I present a new sensing technique in which diacetylene amphiphile containing monomers with unique head group chemistry containing dipicolylamine were used in the detection of lead in liquid phase. The exclusive selectivity of this sensor to lead and the high sensitivity revealed a color change from blue to red upon detection of lead ions in water. In another application, iron containing diacetylene formulations were developed to form the first spray on sensor for the detection of H2O2 vapors in the air. These formulations enabled the catalysis of H2O2 to hydroxyl radicals that served as an initiator in the polymerization of the diacetylene containing amphiphile, causing a white to blue color transition. With this affordable sensing approach, new capabilities open up for the utilization of spray-on sensors for the detection of chemical targets or physical stimuli without the need for training or understanding of complex analytical systems.
Keywords
Diacetylene-based, amphiphile, spray-on, sensor, environmental monitoring, polymer, Pentacosadiynoic acid, self-assembly, dipicolylamine, hydrogen peroxide vapor
Disciplines
Biomedical Engineering and Bioengineering | Polymer and Organic Materials
License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Recommended Citation
Shiveshwarkar, Priyanka, "Spray-On Sensor Formulations That Enable Detection of Physical and Chemical Stimuli" (2024). Bioengineering Dissertations. 122.
https://mavmatrix.uta.edu/bioengineering_dissertations/122
Included in
Biomedical Engineering and Bioengineering Commons, Polymer and Organic Materials Commons