Triglyceride/high Density Lipoprotein Cholesterol Ratio As A Screening Tool For Insulin Resistance In U.S. Adolescents, 12-19 Years Of Age

Author

Constance Elaine Cephus

Graduation Semester and Year

2014

Language

English

Document Type

Dissertation

Degree Name

Doctor of Philosophy in Nursing

Department

Nursing

First Advisor

Jennifer R Gray

Abstract

Background: Insulin resistance appears to be a metabolic process that occurs prior to the onset of cardiovascular disease and type 2 diabetes. A screening tool for insulin resistance may help clinicians determine which adolescents need intensive lifestyle modification to decrease risk of cardiovascular disease and diabetes.Purpose: The purpose of this study is to evaluate the performance characteristics of the TG/HDL ratio when used to assess risk of insulin resistance in U.S. adolescents.Methods: A secondary analysis of 2011-2012 data for adolescents (12-19 years of age) from the National Health and Nutrition Examination Survey (NHANES) was conducted to evaluate the performance characteristics of the TG/HDL ratio. Results: The performance characteristics of the TG/HDL: sensitivity14.8%, specificity 93.8%, positive predictive value 10.4%, negative predictive value 95.8%, overall accuracy 90.2%.Conclusions: These findings indicate that the TG/HDL ratio would be useful to indicate low likelihood of insulin resistance.

Disciplines

Medicine and Health Sciences | Nursing

License

This work is licensed under a Creative Commons Attribution-NonCommercial-Share Alike 4.0 International License.

Comments

Degree granted by The University of Texas at Arlington

Recommended Citation

Cephus, Constance Elaine, "Triglyceride/high Density Lipoprotein Cholesterol Ratio As A Screening Tool For Insulin Resistance In U.S. Adolescents, 12-19 Years Of Age" (2014). Nursing Dissertations. 45.
https://mavmatrix.uta.edu/nursing_dissertations/45