COMPUTATIONAL ANALYSIS OF BLAST INDUCED DAMAGE ON NEURONS IN BRAIN DURING TRAUMATIC BRAIN INJURY

Author

Divya Swamy Bandaru

Graduation Semester and Year

2016

Language

English

Document Type

Thesis

Degree Name

Master of Science in Mechanical Engineering

Department

Mechanical and Aerospace Engineering

First Advisor

Ashfaq Adnan

Abstract

Concussions are the most common kind of brain injuries, they are also called as mild Traumatic Brain Injuries (mTBI). In recent times, mTBIs are perceived as one of the major health problems faced by millions across the world. TBIs occur when there is a sudden acceleration or deceleration force is applied on the human brain that is encapsulated in the skull. When blasts caused by typical IEDs (induced by explosives) in wars propagate through the head, cavitation bubbles are formed in the brain tissue. When these bubbles collapse, they form cavitation-induced shock wave. It has been found that the strains caused by cavitation-induced shock wave are much larger than the strain caused by blasts alone. In previous studies, the effect of cavitation induced shock wave on is studied on the strain rate behavior of brain tissue. In this study, cavitation induced damage is studied on axons of neurons is studied computationally.

Keywords

Traumatic brain injury, Cavitation, Hydrogel, Blast-induced TBI, Brain tissue surrogate

Disciplines

Aerospace Engineering | Engineering | Mechanical Engineering

License

This work is licensed under a Creative Commons Attribution-NonCommercial-Share Alike 4.0 International License.

Comments

Degree granted by The University of Texas at Arlington

Recommended Citation

Bandaru, Divya Swamy, "COMPUTATIONAL ANALYSIS OF BLAST INDUCED DAMAGE ON NEURONS IN BRAIN DURING TRAUMATIC BRAIN INJURY" (2016). Mechanical and Aerospace Engineering Theses. 789.
https://mavmatrix.uta.edu/mechaerospace_theses/789