Document Type

Honors Thesis


Basil plant (Ocimum basilicum) is a common part of the South Asian diet, and it is known to act as an antioxidant after consumption. To understand the potential of basil to relieve oxidative stress and to assess its neuroprotective effect, mouse hippocampal cell line (HT-22) were exposed to ethanol and to basil extracts simultaneously. The toxicity of the hippocampal cells was reduced significantly with the addition of the basil extract, and significantly higher cell viability was detected as compared to the ethanol treated control cells with no basil extract. These data suggest that basil can act as a neuroprotective agent with potential against oxidative stress-induced cell death, potentially leading to aid in neurological disorders that undergo oxidative stress.

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