Document Type
Honors Thesis
Abstract
Basil plant (Ocimum basilicum) is a common part of the South Asian diet, and it is known to act as an antioxidant after consumption. To understand the potential of basil to relieve oxidative stress and to assess its neuroprotective effect, mouse hippocampal cell line (HT-22) were exposed to ethanol and to basil extracts simultaneously. The toxicity of the hippocampal cells was reduced significantly with the addition of the basil extract, and significantly higher cell viability was detected as compared to the ethanol treated control cells with no basil extract. These data suggest that basil can act as a neuroprotective agent with potential against oxidative stress-induced cell death, potentially leading to aid in neurological disorders that undergo oxidative stress.
Publication Date
5-1-2017
Language
English
License
This work is licensed under a Creative Commons Attribution-NonCommercial-Share Alike 4.0 International License.
Recommended Citation
Shihabeddin, Nadine, "NEUROPROTECTIVE EFFECT OF BASIL LEAF EXTRACT ON HIPPOCAMPAL CELL LINE EXPOSED TO ETHANOL" (2017). 2017 Spring Honors Capstone Projects. 18.
https://mavmatrix.uta.edu/honors_spring2017/18