Graduation Semester and Year
Spring 2026
Language
English
Document Type
Thesis
Degree Name
Doctor of Philosophy in Chemistry
Department
Chemistry and Biochemistry
First Advisor
Dr. Junha Jeon
Second Advisor
Dr. Frank Foss
Third Advisor
Dr. Joseph Buonomo
Fourth Advisor
Dr. Rajeshwar Krishnan
Abstract
The selective functionalization of carbon–hydrogen (C–H) and carbon–carbon (C–C) bonds represents a fundamental challenge in modern organic synthesis. Traditional approaches often rely on prefunctionalized substrates or (sub)stoichiometric amounts of basic reagents, resulting in inefficient, less selective, and multi-step processes. In contrast, catalytic strategies that directly transform ubiquitous C–H and C–C bonds offer streamlined and sustainable alternatives. Within this framework, organosilicon chemistry provides a powerful platform due to the unique reactivity and versatility of silicon-containing compounds. Despite considerable progress, the development of general and streamlined approaches for site-selective silicon incorporation through C–H and C–C silylation remains an important unmet need. This dissertation addresses these limitations through the development of redox-divergent catalytic strategies that integrate directing group design, catalyst development, and mechanistic insight.
Keywords
Transition metal catalysis, Silylacetal stabilizing groups, C-H silylation, C-C silylation, Biphenol, Binaphthol, Aniline, Iridium, Rhodium, Sila-acetaminophen
Disciplines
Heterocyclic Compounds | Inorganic Chemicals | Organic Chemicals
License
This work is licensed under a Creative Commons Attribution-NonCommercial-Share Alike 4.0 International License.
Recommended Citation
Adhikary, Suman Das, "REDOX DIVERGENT CATALYTIC C–H AND C–C SILYLATION REACTIONS" (2026). Chemistry & Biochemistry Dissertations. 3.
https://mavmatrix.uta.edu/chemistry_dissertations2/3