Graduation Semester and Year
2019
Language
English
Document Type
Dissertation
Degree Name
Doctor of Philosophy in Chemistry
Department
Chemistry and Biochemistry
First Advisor
Liping Tang
Abstract
Modern technologies have been successfully identifying patient’s disease-related genetic information and developing effective drugs continuously. The discovery of molecular biomarkers paves new roads for potential individualized therapeutic applications; thus far, the call for a more development of advanced targeting/delivery platforms is highly required in the bioengineering field. Unfortunately, bioengineered targeting platforms for drug delivery at the right place, right dosage and right time have still remained in the developmental stages. To develop innovative nanosystems for various biomedical applications, polymer chemistry and click chemistry are needed to improve the function of the nanosystems. My dissertation research is based upon a unique mingling of chemistry and bioengineering. This platform is the perfect example of interdisciplinary research (IDR) and what modern technologies really needs. I believe that the new nanoplatforms and hydrogel scaffolds made here can be used, not only for specific targeting and diagnosis, but also for drug delivery and treatment of various diseases, including cancer, inflammatory disease and cardiovascular disease.
Keywords
Hydrogel polymeric nanoparticle, Click chemistry, Cancer trap, Inflammatory diseases, Cardiovascular diseases
Disciplines
Chemistry | Physical Sciences and Mathematics
License
This work is licensed under a Creative Commons Attribution-NonCommercial-Share Alike 4.0 International License.
Recommended Citation
Khang, Min kyung, "DEVELOPMENT OF INNOVATIVE THERANOSTIC PLATFORMS FOR BIOMEDICAL APPLICATIONS" (2019). Chemistry & Biochemistry Dissertations. 233.
https://mavmatrix.uta.edu/chemistry_dissertations/233
Comments
Degree granted by The University of Texas at Arlington