Anti-viral Capacity Of Quillaja Saponaria Molina Extract Against Vaccinia And Herpes simplex Virus-1
Graduation Semester and Year
2006
Language
English
Document Type
Thesis
Degree Name
Master of Science in Biology
Department
Biology
First Advisor
Michael Roner
Abstract
It is well known that Quillaja saponins have the ability to elicit a strong immune response when used as an adjuvant in an ISCOM matrix. However, to date, the antiviral capability of Quillaja saponins has not been documented. Using extracts from the Chilean Soap Bark Tree (Quillaja Saponaria Molina) we document the anti-viral capacities of Quillaja saponins against HSV-1 and Vaccinia. The saponin was ineffective against Vaccinia Virus, however neutralized HSV-1 in a time and temperature dependent manner. In addition, Quillaja Saponins were determined capable of preventing cell-to-cell spread when introduced in solution to cell monolayers.
Disciplines
Biology | Life Sciences
License
This work is licensed under a Creative Commons Attribution-NonCommercial-Share Alike 4.0 International License.
Recommended Citation
Spinks, Matthew Sean, "Anti-viral Capacity Of Quillaja Saponaria Molina Extract Against Vaccinia And
Herpes simplex Virus-1" (2006). Biology Theses. 27.
https://mavmatrix.uta.edu/biology_theses/27
Comments
Degree granted by The University of Texas at Arlington