Graduation Semester and Year
Spring 2026
Language
English
Document Type
Dissertation
Degree Name
Doctor of Philosophy in Biomedical Engineering
Department
Bioengineering
First Advisor
Liping Tang Ph.D.
Second Advisor
Kytai Nguyen Ph.D.
Third Advisor
Yi Hong Ph.D.
Fourth Advisor
Joseph Borrelli Jr. M.D.
Sixth Advisor
Jon Senkowsky M.D.
Abstract
Prediction of tissue healing is of tantamount importance to injured patients’ wellbeing as well as to physicians’ decision-making process regarding treatment. Biological markers of tissue healing allow physicians to explore new healing treatments or tailor treatments around the healing progress of an injury. This, in turn, reduces decision-making time before patients receive optimal treatment, reducing patient distress and medical costs. In the past 5 years, I have focused on identifying or further confirming biomarkers of healing in human tissue—specifically, in human labral tissues and chronic wounds. My work encompasses both histological studies (chapters 1 and 2) and clinical studies (chapter 3) and has culminated in the publication of the following peer-reviewed articles:
Chapter 1: Hoang LQ, Vaish B, Izuagbe S, et al. Histological Analysis of Regenerative Properties in Human Glenoid Labrum Regions. Am J Sports Med 2023;51(8):2030–2040; doi: 10.1177/03635465231171680.
Chapter 2: Hoang LQ, Rifat S, Gray N, et al. Histological Comparison of Potential Healing Properties in the Human Glenoid and Acetabular Labrum. Orthop J Sports Med 2026. [Manuscript submitted for publication]
Chapter 3: Hoang LQ, Pal S, Liu Z, et al. A time-dependent survival analysis for early prognosis of chronic wounds by monitoring wound alkalinity. Int Wound J 2022;1–17; doi: 10.1111/iwj.14001.
Keywords
glenoid, acetabular, labrum, biomarker, healing, vascularity, chronic wound, regeneration, ulcer, prognosis
Disciplines
Molecular, Cellular, and Tissue Engineering
License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Recommended Citation
Hoang, Le, "Human Tissue-Healing Biomarkers for the Development of Regenerative and Prognostic Products" (2026). Bioengineering Dissertations. 2.
https://mavmatrix.uta.edu/bioengineering_dissertations2/2