Ashley Lutz

Document Type

Honors Thesis


Viruses are a major source of disease in the human population. During infection, viruses can hide inside the body’s cells and avoid detection and eradication by the host’s immune cells. However, the human body has developed several different methods of fighting infections within its cells. This thesis examines the different modes of defense used against viruses during cellular infection, as well as some of the methods viruses use to avoid or subvert the immune system. The literature on immunological defense against viruses was reviewed in order to determine the different methods of defense the human body most often exhibits. While cytotoxic T-cells are most often used to kill virus-infected cells, most cells in the body have internal receptors that allow them to react to viruses in their cells and warn surrounding cells, which initiate their own defenses.

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