Document Type
Article
Source Publication Title
TISSUE ENGINEERING
DOI
http://dx.doi.org/10.1089/ten.2006.0183
Abstract
Diabetes is one of the most prevalent, costly, and debilitating diseases in the world. Although traditional insulin therapy has alleviated the short-term effects, long-term complications are ubiquitous and harmful. For these reasons, alternative treatment options are being developed. This review investigates one appealing area: cell replacement using encapsulated islets. Encapsulation materials, encapsulation methods, and cell sources are presented and discussed. In addition, the major factors that currently limit cell viability and functionality are reviewed, and strategies to overcome these limitations are examined. This review is designed to introduce the reader to cell replacement therapy and cell and tissue encapsulation, especially as it applies to diabetes.
Disciplines
Biomedical Engineering and Bioengineering | Engineering
Publication Date
1-1-2007
Language
English
License
This work is licensed under a Creative Commons Attribution-NonCommercial-Share Alike 4.0 International License.
Recommended Citation
Nguyen, Kytai Truong; Beck, Jonathan; Angus, Ryan; Madsen, Ben; Britt, David; and Vernon, Brent, "Islet encapsulation - Strategies to enhance islet cell functions" (2007). Bioengineering Faculty Publications. 29.
https://mavmatrix.uta.edu/bioengineering_facpub/29
Comments
This is a copy of an article published in the Tissue Engineering ©2007[copyright Mary Ann Liebert, Inc.]; Tissue Engineering is available online at: http://online.liebertpub.com.