Document Type
Honors Thesis
Abstract
In eukaryotes, the structure and function of the Sm core and its associated small nuclear ribonucleoproteins (snRNPs) play a significant role in pre-mRNA splicing. These snRNPs exhibit a high degree of conservation. While plants also utilize alternative splicing, the conservation of plant snRNAs and other non-coding RNA such as snoRNA and scaRNA, which assemble the Sm core, remains largely unexplored. In this study, plant sequences were compared with human sequences using the multiple sequence alignment program Jalview to determine the conservation of snRNPs in other non-coding RNA. Sequences analysis showed that the Sm site in Spinacia oleracea and Arabidopsis thaliana was not well conserved compared to humans. Moreover, low conservation was observed between the two plant species Spinacia oleracea and Arabidopsis thaliana. These findings suggest that snRNA interactions between plants and humans, and between plant species may differ considerably.
Disciplines
Biochemistry | Plant Biology
Publication Date
5-2025
Language
English
Faculty Mentor of Honors Project
Byung Ran So
License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Recommended Citation
Nguyen, Nhi T., "A Comparative Analysis of Small Nuclear RNA Sequences in Spinacia oleracea, Arabidopsis thaliana, and Homo sapiens" (2025). 2025 Spring Honors Capstone Projects. 19.
https://mavmatrix.uta.edu/honors_spring2025/19