ORCID Identifier(s)

0009-0007-2074-1059

Graduation Semester and Year

Spring 2025

Language

English

Document Type

Thesis

Degree Name

Master of Science in Chemistry

Department

Chemistry and Biochemistry

First Advisor

Kevin A Schug

Abstract

Accurate determination of the vapor pressures of organic materials is important for predicting the sample’s environmental impact. It is difficult to directly measure accurate and precise vapor pressures of chemical compounds with direct experimental methods. Thus, indirect or predictive models for estimating vapor pressures are used. In this study, we follow a gas−liquid chromatography (GLC)-based approach, where retention data is correlated with vapor pressure using multiple reference standards. The method (GLC-RTyS) requires temperature-dependent retention factors (k-values) for test compounds and reference standards with known vapor pressures at matching temperatures. It has been observed that reference standards selected according to functional group compatibility are expected to have better estimation accuracy. The study will contribute to vapor pressure modeling methods, which could be a cost and labor-efficient alternative to experimental techniques in environmental scientific fields.

Keywords

GLC-RTyS, retention factor, vapor pressure, gas−liquid chromatography

Disciplines

Analytical Chemistry

License

Creative Commons Attribution 4.0 International License
This work is licensed under a Creative Commons Attribution 4.0 International License.

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